KolossuS


KolossuS predicts kinase-substrate specificity. Given a kinase sequence and a substrate 15-mer sequence (with the 8-th location being Ser,Thr or Tyr), it will predict the probability of their interaction. Combined with a phosphoproetomic screen, and given its speed, KolossuS can be used to screen your phosphopeptides against all human kinases to iden the likely kinases involved in your process of interest. More details are available in our preprint “Deep Learning-coupled Proximity Proteomics to Deconvolve Kinase Signaling In Vivo”.